The semi-variation function of iron grade of the Jijiping ore block of Baima titanomagnetite deposit is analyzed by the major regionalized variables. The corresponding spherical model of semi-variation function is established. The parameters of CO and variances on strike, dip and vertical directions are obtained. The variation coefficients of iron grade in the Jijiping ore block are lower than 0.3, indicating that the mineralization of the orefield is simple and uniform, which is beneficial to mining. According to the statistical analysis, the iron grades display normal distribution, showing that an estimation of ordinary kriging is better than other methods in further research. This investigation provides a theoretical basis for mining planning and production.