The Dongzhongla lead-zinc deposit is one of the newly founded deposits, which lies in the Zhaxue-Yaguila mining area, Nyainqentanglha Range, Tibet. This work has studied the homogeneous temperature, pressure, depth, salinities and compositions in quartz and calcspar in various mineralization stages of the hydrothermal ore-forming process of this deposit. The result indicates that the ore fluids belong to low and medium temperature, low sality, low and medium density and the Cl--SO42--K+-Na+ hydrochemical type.