According to research achievement of mineral exploration in depth of Xiaoqinling gold deposit region and prospecting practice for Chen’er gold ore deposit, it concluded that Xiaoqinling gold deposit region is another super-large ore cluster region, which has superior exploration condition and potential in depth. On the base of strengthening geology synthetical study and understanding metallogenic regularity, the effective methods for exploration in depth includes geology, geophysics, and geochemistry comprehensive new techniques, and so on. It can forecast deep enriched section of orebody by using the geochemical axis zoned model, and prove by drill project in hole.