The paper analyzes the impacts of intensive tectonic compression on natural gas migration and accumulation in the later Himalayan period, taking the Kela 2 gas field in the Kuqa foreland basin as an example. Tectonic compression makes the fluid pressure rapidly increase and changes the previous relatively stable fluid potential field. The accumulation gas near the fault zones rapidly migrates towards upper strata along the opening faults and charges laterally the sand bodies located under the regional cap rock, accumulates in the lower gas potential area. The study for impact of tectonic compression on natural gas accumulation has important theory and application for guiding oil and gas exploration in foreland basin.