line-height-rule: exactly" class=MsoNormal>The zircon U-Pb and Molybdenites Re-Os ages are reported in this paper, with the bulk-rock major element, trace element and zircon Hf isotopic data on the ore-bearing rocks in Chagele deposit. This paper suggests that the Late Cretaceous magmatism and mineralization in middle of the Gangdise metallogenic belt could be produced by partial melting of ancient crust materials of the Lhasa microcontinent accompanying with fractional crystallization, which are probably induced by underplating of mantle-derived magmas in the main collision setting of the collision between Indian and Eurasia.  The authors also believe that the zonation of the ore-forming element in the Gangdise metallogenic belt is associated with source material of magma during subduction or collision process of the Neo-Tethyan oceanic.