The Taiwushan granite pluton, with an outcropped area of about 40 km<SUP>2, is roughly elongated NE-trending as an irregular stock in the coastal region of SE Fujian Province. Zircon LA-ICP-MS U-Pb dating yields an age of (96.9±1.3) Ma（MSWD=1.09, 2σ）,  indicating that this pluton was generated in the initial stage of Late Cretaceous. Based on a synthesis of geology, geochronology, elemental and isotopic geochemistry, the authors suggest that the Taiwushan granites were most likely generated via a two-stage process including formation of parental magma by mixing of a depleted mantle-derived magma and an induced crustal-melted felsic magma in the deep crust, and then suffered further differentiation during magma ascent.