Gas hydrate has been recognized to be a potential energy resource in the South China Sea minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">(SCSminor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">) and the acoustic response of gas hydrate formations in the SCS sediments is of significance in the regional hydrate investigation and quantification. We conducted a simulation experiment to investigate the acoustic response of hydrate formations in the Shenhu area of the SCS using a new bender- element detection technique combined with the casing time-domain reflectometry minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">(TDRminor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">). The results showed that the acoustic signal becomes weaker with the occurrence of hydrates as the saturation of hydrates minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">(Shminor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">) ranges from 0 to 14% ; then it strengthens gradu- ally as Sh is higher than 14%. The acoustic velocities minor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">(vp, vsminor-latin; mso-fareast-font-family: 宋体; mso-fareast-theme-font: minor-fareast; mso-hansi-font-family: calibri; mso-hansi-theme-font: minor-latin">) of sediments increase with the increase of Sh during hydrate formation and vs increases relatively faster as Sh becomes higher than 14%. These phenomena indicated that hydrates may form firstly in pore fluids in the form of tiny particles, which results in a weaker acoustic signal due to the considerable scattering attenuation of acoustic wave, but has little effect on shear modulus. As time lapses, when Sh exceeds 14%, numerous tiny particles of hydrates coalesce to- gether and contact with sediment particles. As a result, vs has a sharp increase.