The characteristics of reservoir lithology and petrophysical property as well as serious heterogeneity of the target zones in studied area are introduced in this paper. The results show that the heterogeneity is mainly influenced by weathering interface, lithology, lithofacies and fractures. In vertical, the effect of unconformity depth on heterogeneity is a key factor, and for the same depth, it is influenced by the lithology and dissolution, while the fractures expand the connectivity and scale of reservoir dissolution.