In order to find out the hydrocarbon-generating potential of Permian source rocks in Wuli permafrost zone,Qinghai-Tibetan Plateau,the cores from gas-hydrate trial hole (ZK1)and its adjacent drilling holes were analyzed.The results show that the organic matter abundance of upper member source rocks of Nayixiong For-mation in Upper Permian is poor,while the abundance of the lower member is fair to good.The organic type is mainly constituted by Ⅲ kerogen,which is in favor of generating gas.The thermal evolution degree of Permian source rocks is very high,reaching to excessive maturity.Considering that the maturity of mudstone and meta-morphic grade of coal bed are very high in Wuli Permafrost zone,it can be drawn a conclusion that the hydro-carbon-generating potential of Permian source rocks is general good in Wuli permafrost zone,Qinghai-Tibetan Plateau.