Construction of Hexahydropyrido[3,2-c]carbazole and Hexahydropyrrolo[3,2-c]carbazole Skeletons for the Synthesis of Related Indole Alkaloids

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• 作者：Cevher Gü ; ndoğdu Hızlıateş and Sibel Gü ; lle
• 刊名：Journal of Heterocyclic Chemistry
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：53
• 期：5
• 页码：1584-1588
• 全文大小：260K
• ISSN：1943-5193

文摘

Synthesis of tetracyclic hexahydropyrido[3,2-c]carbazoles (href="#jhet2467-eo-0011" rel="references:#jhet2467-eo-0011"> and href="#jhet2467-eo-0012" rel="references:#jhet2467-eo-0012">) and hexahydropyrrolo[3,2-c]carbazoles (href="#jhet2467-eo-0016" rel="references:#jhet2467-eo-0016"> and href="#jhet2467-eo-0017" rel="references:#jhet2467-eo-0017">) structures was achieved via a new synthetic approach for the synthesis of related indole alkaloids such as deethylaspidospermidine and deethylibophyllidine. Hexahydropyrrolo[3,2-c]carbazole structure was constructed for the first time starting from http://www.wiley.com/namespaces/wiley" xmlns:cr="urn://wiley-online-library/content/render" xmlns:mml="http://www.w3.org/1998/Math/MathML" id="jhet2467-eo-2003">ethyl 4-oxo-cyclohexanecarboxylate in seven steps. Some tetrahydrocarbazole derivatives (href="#jhet2467-eo-0006" rel="references:#jhet2467-eo-0006">, href="#jhet2467-eo-0007" rel="references:#jhet2467-eo-0007">, href="#jhet2467-eo-0008" rel="references:#jhet2467-eo-0008">, href="#jhet2467-eo-0009" rel="references:#jhet2467-eo-0009">, href="#jhet2467-eo-0014" rel="references:#jhet2467-eo-0014">, and href="#jhet2467-eo-0015" rel="references:#jhet2467-eo-0015">) were also synthesized.