fMRI brain activation changes following treatment of a first bipolar manic episode
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- 作者：Stephen M Strakowski ; David E Fleck ; Jeffrey Welge ; James C Eliassen ; Matthew Norris ; Michelle Durling ; Richard A Komoroski ; Wen-Jang Chu ; Wade Weber ; Jonathan A Dudley ; Thomas J Blom ; Amanda Stover ; Christina Klein ; Jeffrey R Strawn ; Melissa P DelBello ; Jing-Huei Lee and Caleb M Adler
- 刊名：Bipolar Disorders
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：18
- 期：6
- 页码：490-501
- 全文大小：970K
- ISSN：1399-5618
文摘
We tested the hypothesis that, with treatment, functional magnetic resonance imaging (fMRI) regional brain activation in first-episode mania would normalize – i.e., that differences from healthy subjects would diminish over time, and would be associated with clinical remission status, potentially identifying neuroanatomic treatment response markers.