An Agostic Iridium Pincer Complex as a Highly Efficient and Selective Catalyst for Monoisomerization of 1-Alkenes to trans-2-Alkenes

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• 作者：Yulei Wang ; Chuan Qin ; Xiangqing Jia ; Xuebing Leng and Prof. Dr. Zheng Huang
• 刊名：Angewandte Chemie International Edition
• 出版年：2017
• 出版时间：February 1, 2017
• 年：2017
• 卷：56
• 期：6
• 页码：1614-1618
• 全文大小：1127K
• ISSN：1521-3773

文摘

A unique Ir complex (^tBuNC^CP)Ir with the pyridine–phosphine pincer as the sole ligand, featuring a dual agostic interaction between the Ir and two σ C−H bonds from a tBu substituent, has been prepared. This complex exhibits exceptionally high activity and excellent regio- and stereoselectivity for monoisomerization of 1-alkenes to trans-2-alkenes with wide functional-group tolerance. Reactions can be performed in neat reactant on a more than 100 gram scale using 0.005 mol % catalyst loadings with turnover numbers up to 19000.