Clinical analysis of 1629 newly diagnosed malignant lymphomas in current residents of Sichuan province, China

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• 作者：Xue-mei Wang ; Bryan A. Bassig ; Jing-jing Wen ; Gan-di Li ; Zhi-bin Liu ; Wen-xiu Yao ; Wei Hu ; Ying Wang ; Ji-man Li ; Xiao-dong Wang ; Mao-zhou Gan ; Chun-sen Wang ; Gang Xu ; Nathaniel Rothman ; Qing Lan and Cai-gang Xu
• 刊名：Hematological Oncology
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：34
• 期：4
• 页码：193-199
• 全文大小：198K
• ISSN：1099-1069

文摘

Previous studies in other provinces of China (Beijing, Xinjiang, Shanxi, Jiangxi, Shanghai, Guangdong, and Taiwan) suggest that the distributions of lymphoma subtypes differ compared with Western populations. In order to evaluate the characteristics of malignant lymphoma in Sichuan, China, we analyzed case series data from incident lymphoma patients diagnosed in 2008 from three hospitals, including a total of 1629 cases and including only current residents of Sichuan. The median age of diagnosis for cases was 54 years, with a higher proportion of male cases compared with female cases. The most commonly diagnosed subtypes included diffuse large B-cell lymphoma (40.4%), NK/T-cell lymphoma (NKTCL; 11.8%), mixed cellularity Hodgkin lymphoma (7.0%), mantle cell lymphoma (4.8%), and marginal zone B-cell lymphoma (3.9%). Differences in demographic characteristics between Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) cases were apparent for median age at diagnosis (HL: 34 years; NHL: 57 years), and NHLs accounted for nearly all (99.3%) of the 931 cases of extranodal lymphoma. These findings indicate a higher proportion of NKTCL cases and a lower proportion of follicular lymphoma cases (2.3%) in these hospitals in Sichuan, relative to reports from some other provinces within China (e.g., Shanghai and Shanxi) and the USA. Copyright