The development of sustained release drug delivery platforms using melt-extruded cellulose-based polymer blends

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• 作者：Matthew R. Wilson ; David S. Jones and Gavin P. Andrews
• 刊名：Journal of Pharmacy and Pharmacology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：69
• 期：1
• 页码：32-42
• 全文大小：780K
• ISSN：2042-7158

文摘

This research examined the application of hot melt extrusion (HME) in the preparation of matrix formulations containing hydroxypropyl cellulose (HPC) as a base polymer in combination with methyl cellulose (MC) and hydroxypropyl methylcellulose (HPMC).