Copper-Catalyzed Amidation of Primary and Secondary Alkyl Boronic Esters
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- 作者：Dr. Luis M. Mori-Quiroz ; Kirk W. Shimkin ; Dr. Sina Rezazadeh ; Ryan A. Kozlowski and Prof. Dr. Donald A. Watson
- 刊名：Chemistry - A European Journal
- 出版年：2016
- 出版时间：October 24, 2016
- 年：2016
- 卷：22
- 期：44
- 页码：15654-15658
- 全文大小：586K
- ISSN：1521-3765
文摘
The oxidative copper-catalyzed cross-coupling of functionalized alkyl boronic esters with primary amides is reported. Through the identification of appropriate diketimine ligands, conditions for efficient coupling of both primary and secondary alkyl boronic esters with diverse primary amides, including acetamide, have been developed.