Cellulose Biorefinery Based on a Combined Catalytic and Biotechnological Approach for Production of 5-HMF and Ethanol

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• 作者：Dr. Ksenia N. Sorokina ; Prof. Oxana P. Taran ; Tatiana B. Medvedeva ; Yuliya V. Samoylova ; Alexandr V. Piligaev and Prof. Valentin N. Parmon
• 刊名：ChemSusChem
• 出版年：2017
• 出版时间：February 8, 2017
• 年：2017
• 卷：10
• 期：3
• 页码：562-574
• 全文大小：1775K
• ISSN：1864-564X

文摘

In this study, a combination of catalytic and biotechnological processes was proposed for the first time for application in a cellulose biorefinery for the production of 5-hydroxymethylfurfural (5-HMF) and bioethanol. Hydrolytic dehydration of the mechanically activated microcrystalline cellulose over a carbon-based mesoporous Sibunt-4 catalyst resulted in moderate yields of glucose and 5-HMF (21.1–25.1 and 6.6–9.4 %). 5-HMF was extracted from the resulting mixture with isobutanol and subjected to ethanol fermentation. A number of yeast strains were isolated that also revealed high thermotolerance (up to 50 °C) and resistance to inhibitors found in the hydrolysates. The strains Kluyveromyces marxianus C1 and Ogataea polymorpha CBS4732 were capable of producing ethanol from processed catalytic hydrolysates of cellulose at 42 °C, with yields of 72.0±5.7 and 75.2±4.3 % from the maximum theoretical yield of ethanol, respectively.