Disease control and toxicity outcomes for T4 carcinoma of the nasopharynx treated with intensity-modulated radiotherapy

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• 作者：Vinita Takiar ; Dominic Ma ; Adam S. Garden ; Jing Li ; David I. Rosenthal ; Beth M. Beadle ; Steven J. Frank ; Clifton D. Fuller ; Gary B. Gunn ; William H. Morrison ; Kate Hutcheson ; Adel K. El-Naggar ; Kathryn A. Gold ; Michael E. Kupferman and Jack Phan
• 关键词：nasopharyngeal carcinoma ; toxicities ; intensity-modulated radiation therapy (IMRT) ; chemotherapy ; temporal lobe necrosis
• 刊名：Head & Neck
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：38
• 期：S1
• 页码：E925-E933
• 全文大小：2096K
• ISSN：1097-0347

文摘

Treatment of T4 nasopharyngeal carcinoma (NPC) is challenging because of the proximity of the tumor to the central nervous system. The purpose of this study was to present our evaluation of disease control and toxicity outcomes for patients with T4 NPC treated with intensity-modulated radiation therapy (IMRT) and chemotherapy.