Prediction of response to tapentadol in chronic low back pain
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- 作者：M. Reimer ; P. Hü ; llemann ; M. Hukauf ; T. Keller ; A. Binder ; J. Gierthmü ; hlen and R. Baron
- 刊名：European Journal of Pain
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：21
- 期：2
- 页码：322-333
- 全文大小：395K
- ISSN：1532-2149
文摘
Many chronic low back pain (cLBP) patients do not satisfactorily respond to treatment. The knowledge of responders and non-responders before initiating treatment would improve decision making and reduce health care costs. The aims of this exploratory prediction study in cLBP patients treated with tapentadol were to identify predictors of treatment outcome based on baseline characteristics, to evaluate quality-of-life and functionality as alternative outcome parameters and to develop nomograms to calculate the individual probability of response.