An Injectable Self-Assembling Collagen-Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy

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• 作者：Ruirui Xing ; Kai Liu ; Tifeng Jiao ; Ning Zhang ; Kai Ma ; Ruiyun Zhang ; Qianli Zou ; Guanghui Ma and Xuehai Yan
• 刊名：Advanced Materials
• 出版年：2016
• 出版时间：May 18, 2016
• 年：2016
• 卷：28
• 期：19
• 页码：3669-3676
• 全文大小：1635K
• ISSN：1521-4095

文摘

An injectable and self-healing collagen–gold hybrid hydrogel is spontaneously formed by electrostatic self-assembly and subsequent biomineralization. It is demonstrated that such collagen-based hydrogels may be used as an injectable material for local delivery of therapeutic agents, showing enhanced antitumor efficacy.