Metal-Organic-Framework-Derived Mesoporous Carbon Nanospheres Containing Porphyrin-Like Metal Centers for Conformal Phototherapy
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- 作者：Shunhao Wang ; Lu Shang ; Linlin Li ; Yingjie Yu ; Chongwei Chi ; Kun Wang ; Jie Zhang ; Run Shi ; Heyun Shen ; Geoffrey I. N. Waterhouse ; Sijin Liu ; Jie Tian ; Tierui Zhang and Huiyu Liu
- 刊名：Advanced Materials
- 出版年：2016
- 出版时间：October 12, 2016
- 年：2016
- 卷：28
- 期：38
- 页码：8379-8387
- 全文大小：2883K
- ISSN：1521-4095
文摘
Mesoporous carbon nanospheres containing porphyrin-like metal centers (denoted as “PMCS”) are successfully synthesized by the pyrolysis of an imidazolate framework using a mesoporous-silica protection strategy. The PMCS allow infrared and photoacoustic imaging and synergetic photothermal therapy/photodynamic therapy derived from the porphyrin-like moieties, offering the possibility of real-time monitoring of therapeutic processes and image-guided precise conformal phototherapy. PMCS thus represent a novel multifunctional theranostic platform for improved treatment efficiencies.