Intrinsic resistance to sunitinib in patients with metastatic renal cell carcinoma
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- 作者：Sung Hee Lim ; In Gyu Hwang ; Jun Ho Ji ; Sung Yong Oh ; Jun Ho Yi ; Do Hyoung Lim ; Ho Yeong Lim ; Su Jin Lee and Se Hoon Park
- 刊名：Asia-Pacific Journal of Clinical Oncology
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：13
- 期：1
- 页码：61-67
- 全文大小：188K
- ISSN：1743-7563
文摘
Although targeting angiogenesis with vascular endothelial growth factor receptor (VEGFR) inhibitors has demonstrated efficacy in the treatment of renal cell carcinoma, primary, intrinsic resistance to the VEGFR inhibitor sunitinib is not fully understood in a subset of metastatic RCC (mRCC) patients.