Inside Cover: Deeper Insight into the Diels-Alder Reaction through the Activation Strain Model (Chem. Asian J. 23/2016)

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• 作者：Dr. Israel Fern&aacute ; ndez and Prof. Dr.  F. Matthias Bickelhaupt
• 刊名：Chemistry – An Asian Journal
• 出版年：2016
• 出版时间：December 6, 2016
• 年：2016
• 卷：11
• 期：23
• 页码：3291
• 全文大小：1543K
• ISSN：1861-471X

文摘

The Diels–Alder (DA) cycloaddition reaction has the ability to significantly increase molecular complexity regioselectively and stereospecifically in a single synthetic step. In this review it is discussed how the activation strain model of chemical reactivity reveals the physical factors that determine the course of Diels–Alder reactivity using recent, representative examples that cover a wide range of issues, such as the “endo-rule”, reactivity trends emerging from systematic variation in the reactants′ strain, and cycloaddition reactions involving relevant species in materials science (i.e., fullerenes, polycyclic aromatic hydrocarbons and nanotubes). More information can be found in the Focus Review by Fernández and Bickelhaupt on page 3297 in Issue 23, 2016 (DOI: 10.1002/asia.201601203).