Individual differences in cognitive reappraisal use and emotion regulatory brain function in combat-exposed veterans with and without PTSD

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• 作者：Jacklynn M. Fitzgerald ; Annmarie MacNamara ; Amy E. Kennedy ; Christine A. Rabinak ; Sheila A.M. Rauch ; Israel Liberzon and K. Luan Phan
• 刊名：Depression and Anxiety
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：34
• 期：1
• 页码：79-88
• 全文大小：286K
• ISSN：1520-6394

文摘

Veterans with posttraumatic stress disorder (PTSD) exhibit marked deficits in emotion regulation. Past research has demonstrated underengagement of the prefrontal cortex during regulation of negative affect in those with PTSD, but has been unable to find evidence of impaired downregulation of the amygdala. One possibility is that there exists variability in amygdala reactivity that cuts across diagnostic status and which can be characterized using a continuous measure of individual differences. In healthy/nontraumatized volunteers, individual variability in amygdala engagement during emotion processing and regulation has been shown to relate to habitual use of regulation strategies.