A significant effect of the killer cell immunoglobulin-like receptor ligand human leucocyte antigen-C on fibrosis progression in chronic C hepatitis with or without liver transplantation
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- 作者：Sté ; phane Buhler ; Emiliano Giostra ; Corinne Gbame ; Casimir de Rham ; Beat Mullhaupt ; Jean-Franç ; ois Dufour ; Pietro Majno ; Francesco Negro ; Pierre-Yves Bochud ; Jean Villard and on behalf of the Swiss Hepatitis C Cohort Study (SCCS) and Swiss Transplant Cohort Study (STCS)
- 刊名：Liver International
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：36
- 期：9
- 页码：1331-1339
- 全文大小：230K
- ISSN：1478-3231
文摘
The interaction of killer cell immunoglobulin–like receptors with their human leucocyte antigen ligands drives the activation and inhibition of natural killer cells. Natural killer cells could be implicated in the development of liver fibrosis in chronic hepatitis C.