Hypoxia-inducible factor-2α promotes hepatocyte apoptosis during cholestasis

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• 作者：Xiangwei Hua ; Tianfei Lu ; Jiang Zhang ; Qi Miao ; Zhaolian Bian ; Haiyan Zhang ; Shanshan Huang ; Weiwei Lin ; Zhifeng Xi ; Ming Zhang ; Qimin Chen ; Xiong Ma ; Jianjun Zhang and Qiang Xia
• 刊名：Hepatology Research
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：47
• 期：1
• 页码：95-102
• 全文大小：735K
• ISSN：1872-034X

文摘

Hypoxia-inducible factor-2α (HIF-2α) has been reported to play an important role in a host of pathophysiological processes, including cellular survival. This study explores the role of HIF-2α in cholestasis-mediated hepatocyte apoptosis.