ChemInform Abstract: Unexpected Isocyanide-Based Three-Component Bicyclization for the Stereoselective Synthesis of Densely Functionalized Pyrano[3,4-c]pyrroles.
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- 作者：Qian Gao ; Wen-Juan Hao ; Feng Liu ; Shu-Jiang Tu ; Shu-Liang Wang ; Guigen Li and Bo Jiang
- 关键词：pyran derivatives ; fused pyrrole derivatives ; ring closure reactions ; annulation reactions ; diastereoselective syntheses ; enantioselective syntheses (incl. cis/trans-isomerism)
- 刊名：ChemInform
- 出版年：2016
- 出版时间：April, 2016
- 年：2016
- 卷：47
- 期：20
- 全文大小：25K
- ISSN：1522-2667
文摘
A novel three-component bicyclization strategy for the efficient synthesis of diversely substituted pyrano[3,4-c]pyrroles is presented starting from readily accessible 3-aroylacrylic acids, dialkyl acetylenedicarboxylates, and isocyanides.