Efficient tumor eradication by endogenous synergistic cancer therapy has been developed by combining NO gas therapy with starvation of tumor cells. In their Communication on
page 1229 ff., P. Huang, T. Wang, X. Chen et al. describe a biocompatible porous nanocapsule formula made of an organosilicate that transports g
lucose oxidase and
l-arginine into tumor cells simultaneously. This g
lucose-responsive nanomedicine shows sequential generation of H
2O
2 and NO.