Core-Shell Gold Nanorod@Metal-Organic Framework Nanoprobes for Multimodality Diagnosis of Glioma

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• 作者：Wenting Shang ; Chaoting Zeng ; Yang Du ; Hui Hui ; Xiao Liang ; Chongwei Chi ; Kun Wang ; Zhongliang Wang and Jie Tian
• 刊名：Advanced Materials
• 出版年：2017
• 出版时间：January 18, 2017
• 年：2017
• 卷：29
• 期：3
• 全文大小：3247K
• ISSN：1521-4095

文摘

One of the most significant challenges in the diagnosis of brain cancer is efficient in vivo imaging using nontoxic nanoprobes. Core–shell gold nanorod@MIL-88(Fe) nanostars are successfully constructed as triple-modality imaging (computed tomography/magnetic-resonance imaging/photoacoustic imaging) nanoprobes that show low cytotoxicity, high contrast, high penetration depth, and high spatial resolution for accurate and noninvasive imaging and diagnosis of gliomas.