The role of the gastrointestinal microbiome in infectious complications during induction chemotherapy for acute myeloid leukemia
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- 作者：Jessica R. Galloway-Peñ ; a ; Daniel P. Smith ; Pranoti Sahasrabhojane ; Nadim J. Ajami ; W. Duncan Wadsworth ; Naval G. Daver ; Roy F. Chemaly ; Lisa Marsh ; Shashank S. Ghantoji ; Naveen Pemmaraju ; Guillermo Garcia-Manero ; Katayoun Rezvani ; Amin M. Alousi ; Jennifer A. Wargo ; Elizabeth J. Shpall ; Phillip A. Futreal ; Michele Guindani ; Joseph F. Petrosino ; Dimitrios P. Kontoyiannis and Samuel A. Shelburne
- 刊名：Cancer
- 出版年：2016
- 出版时间：July 15, 2016
- 年：2016
- 卷：122
- 期：14
- 页码：2186-2196
- 全文大小：647K
- ISSN：1097-0142
文摘
Despite increasing data on the impact of the microbiome on cancer, the dynamics and role of the microbiome in infection during therapy for acute myelogenous leukemia (AML) are unknown. Therefore, the authors sought to determine correlations between microbiome composition and infectious outcomes in patients with AML who were receiving induction chemotherapy (IC).