Reduced peripheral blood mtDNA content is associated with impaired glucose-stimulated islet β cell function in a Chinese population with different degrees of glucose tolerance
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- 作者：Mei-cen Zhou ; Lixin Zhu ; Xiangli Cui ; Linbo Feng ; Xuefeng Zhao ; Shuli He ; Fan Ping ; Wei Li and Yuxiu Li
- 刊名：Diabetes/Metabolism Research and Reviews
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：32
- 期：7
- 页码：768-774
- 全文大小：143K
- ISSN：1520-7560
文摘
Our aim is to explore the associations between mitochondrial DNA (mtDNA) content and basal plasma glucose, plasma glucose after oral glucose administration and oxidative stress in a Chinese population with different levels of glucose tolerance. We also aimed to investigate the effect of mtDNA content on basal and oral glucose-stimulated insulin secretion.