Dexamethasone promotes long-term functional recovery of neuromuscular junction in a murine model of tourniquet-induced ischaemia-reperfusion

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• 作者：D. Zhang ; D. Wang ; I. I. Pipinos ; R. L. Muelleman and Y.-L. Li
• 刊名：Acta Physiologica
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：219
• 期：2
• 页码：453-464
• 全文大小：1202K
• ISSN：1748-1716

文摘

Tourniquet-induced ischaemia and subsequent reperfusion cause serious ischaemia–reperfusion (IR) injury in the neuromuscular junction (NMJ) and skeletal muscle. Here, we investigated whether dexamethasone (Dex) promotes long-term functional recovery of the NMJ and skeletal muscle in tourniquet-induced hindlimb IR.