ChemInform Abstract: Sequential Substitution/Ring Cleavage/Addition Reaction of 1-(Cyclohex-1-enyl)-piperidine and -pyrrolidine with Chloropyruvates for the Efficient Synthesis of Substituted 4,5,6,7-Tetrahydro-1H-indole Derivatives.
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- 作者：Vakhid A. Mamedov ; Elena A. Hafizova ; Anastasiya I. Zamaletdinova ; Il' ; dar Kh. Rizvanov ; Alla B. Mirgorodskaya ; Lucia Ya. Zakharova ; Shamil K. Latypov and Oleg G. Sinyashin
- 关键词：indole derivatives ; isoindole derivatives ; cascade reactions ; domino reactions ; tandem reactions
- 刊名：ChemInform
- 出版年：2016
- 出版时间：March, 2016
- 年：2016
- 卷：47
- 期：13
- 全文大小：29K
- ISSN：1522-2667
文摘
The preparation of the required enamine in-situ from cyclohexenone and pyrrolidine is shown, thus leading to an efficient sequential three-component heteroannulation reaction.