Frontispiece: Association and Dissociation of Grignard Reagents RMgCl and Their Turbo Variant RMgClLiCl

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• 作者：Christoph Schnegelsberg ; Sebastian Bachmann ; Marlene Kolter ; Thomas Auth ; Dr. Michael John ; Prof. Dr. Dietmar Stalke and Prof. Dr. Konrad Koszinowski
• 刊名：Chemistry - A European Journal
• 出版年：2016
• 出版时间：June 1, 2016
• 年：2016
• 卷：22
• 期：23
• 全文大小：4510K
• ISSN：1521-3765

文摘

Grignard Reagents Grignard reagents RMgCl and their so-called turbo variant RMgCl⋅LiCl are of exceptional synthetic utility, but it remains unclear which species these compounds form in solution and, in particular, in which way LiCl exerts its reactivity-enhancing effect. In their Full Paper on page 7752 ff., K. Koszinowski et al. report the use of a combination of four techniques to analyze solutions of various RMgCl species in ethereal solvents in the absence and presence of LiCl. Some of the Grignard reagent forms anionic ate complexes in solution, the abundance of which strongly increases upon addition of LiCl, thus rationalizing its beneficial effect on the reactivity.