Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture
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- 作者：Marta E. Alarcó ; n-Riquelme ; Julie T. Ziegler ; Julio Molineros ; Timothy D. Howard ; André ; s Moreno-Estrada ; Elena Sá ; nchez-Rodrí ; guez ; Hannah C. Ainsworth ; Patricia Ortiz-Tello ; Mary E. Comeau ; Astrid Rasmussen ; Jennifer A. Kelly ; Adam Adler ; Eduardo M. Acevedo-Vá ; zquez ; Jorge Mariano Cucho-Venegas ; Ignacio Garcí ; a-De la Torre ; Mario H. Cardiel ; Pedro Miranda ; Luis J. Catoggio ; Marco Maradiaga-Ceceñ ; a ; Patrick M. Gaffney ; Timothy J. Vyse ; Lindsey A. Criswell ; Betty P. Tsao ; Kathy L. Sivils ; Sang-Cheol Bae ; Judith A. James ; Robert P. Kimberly ; Kenneth M. Kaufman ; John B. Harley ; Jorge A. Esquivel-Valerio ; José ; F. Moctezuma ; Mercedes A. Garcí ; a ; Guillermo A. Berbotto ; Alejandra M. Babini ; Hugo Scherbarth ; Sergio Toloza ; Vicente Baca ; Swapan K. Nath ; Carlos Aguilar Salinas ; Lorena Orozco ; Teresa Tusié ; -Luna ; Raphael Zidovetzki ; Bernardo A. Pons-Estel ; Carl D. Langefeld and Chaim O. Jacob
- 刊名：Arthritis & Rheumatism
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：68
- 期：4
- 页码：932-943
- 全文大小：363K
- ISSN：1529-0131
文摘
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a strong genetic component. We undertook the present work to perform the first genome-wide association study on individuals from the Americas who are enriched for Native American heritage.