Impact of aldo-keto reductase family 1 member B10 on the risk of hepatitis C virus-related hepatocellular carcinoma
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- 作者：Shunsuke Sato ; Takuya Genda ; Takafumi Ichida ; Ayato Murata ; Hironori Tsuzura ; Yutaka Narita ; Yoshio Kanemitsu ; Sachiko Ishikawa ; Tetsu Kikuchi ; Masashi Mori ; Katsuharu Hirano ; Katsuyori Iijima ; Ryo Wada ; Akihito Nagahara and Sumio Watanabe
- 刊名：Journal of Gastroenterology and Hepatology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：31
- 期：7
- 页码：1315-1322
- 全文大小：646K
- ISSN：1440-1746
文摘
Aldo-keto reductase family 1 member B10 (AKR1B10), a cancer-related oxidoreductase, was recently reported to be upregulated in some chronic liver diseases. However, its relevance in hepatocellular carcinoma (HCC) development is not fully assessed, especially in patients with chronic hepatitis C virus (HCV) infection.