Anti-inflammatory effects of intranasal cyclosporine for allergic rhinitis in a mouse model

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• 作者：Yeon-Hee Joo ; Dong-Yeop Chang ; Jin Hyun Kim ; Myeong Hee Jung ; Jino Lee ; Hyun-Jin Cho ; Sea-Yuong Jeon ; Seong-Jae Kim and Sang-Wook Kim
• 刊名：International Forum of Allergy & Rhinology
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：6
• 期：11
• 页码：1139-1144
• 全文大小：582K
• ISSN：2042-6984

文摘

Although topical corticosteroids are considered a safe and effective drug for allergic rhinitis (AR), some AR patients do not show sufficient symptomatic improvement by use of topical corticosteroids. Topical cyclosporine is a safe and effective drug for patients with allergic conjunctivitis, particularly for those with steroid-resistant allergic conjunctivitis. We investigated the anti-inflammatory effects of intranasal cyclosporine for AR using a mouse model.