Laparoscopic surgery for patients with colorectal cancer produces better short-term outcomes with similar survival outcomes in elderly patients compared to open surgery

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• 作者：Soo Yun Moon ; Sohee Kim ; Soo Young Lee ; Eon Chul Han ; Sung-Bum Kang ; Seung-Yong Jeong ; Kyu Joo Park ; Jae Hwan Oh and On behalf of the SEoul COlorectal Group (SECOG)
• 刊名：Cancer Medicine
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：5
• 期：6
• 页码：1047-1054
• 全文大小：136K
• ISSN：2045-7634

文摘

The number of operations on elderly colorectal cancer (CRC) patients has increased with the aging of the population. The aim of this study was to evaluate surgical outcomes in elderly patients who underwent laparoscopic or open surgery for CRC. We analyzed the data of 280 patients aged 80 or over who underwent surgery for CRC between January 2001 and December 2010. Seventy-one pairs were selected after propensity score matching for laparoscopic or open surgery. Operative time, return to normal bowel function, length of hospital stay, postoperative complications, overall survival (OS), recurrence-free survival (RFS), and prognostic factors affecting survival were investigated. In matched cohorts, operative time in the laparoscopic group was longer than in the open group (P < 0.001). In the laparoscopic group, time to flatus passage (P < 0.001) and length of postoperative hospital stay (P = 0.037) were shorter than in the open group. The rate of operation-related morbidity was higher in the open group (P = 0.019). There was no difference in OS and RFS between two groups. This study suggests that laparoscopic surgery for CRC in elderly patients may be safe and feasible, with better short-term outcomes. OS and RFS, however, were not different in both groups.