Immunohistochemical differentiation of eosinophilic esophageal myositis from eosinophilic esophagitis

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• 作者：Hiroki Sato ; Nao Nakajima ; Go Hasegawa ; Yuzo Kawata ; Yuichi Sato ; Kenji Suzuki ; Terasu Honma and Shuji Terai
• 刊名：Journal of Gastroenterology and Hepatology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：32
• 期：1
• 页码：106-113
• 全文大小：1206K
• ISSN：1440-1746

文摘

Eosinophilic esophagitis (EoE) is a Th2-mediated allergic disease of the esophageal epithelium, associated with antigen. We previously reported a case series for eosinophilic esophageal myositis (EoEM)—a novel eosinophilic gastrointestinal disorder defined as eosinophilic infiltration localized in the esophageal muscle layer—and diagnosed it by peroral endoscopic muscle biopsy. Here, we investigated the immunopathology of EoEM to differentiate it from EoE.