Diagnostics: High Performance, Multiplexed Lung Cancer Biomarker Detection on a Plasmonic Gold Chip (Adv. Funct. Mater. 44/2016)
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- 作者：Bin Liu ; Yaling Li ; Hao Wan ; Lin Wang ; Wei Xu ; Shoujun Zhu ; Yongye Liang ; Bo Zhang ; Jiatao Lou ; Hongjie Dai and Kun Qian
- 刊名：Advanced Functional Materials
- 出版年：2016
- 出版时间：November 22, 2016
- 年：2016
- 卷：26
- 期：44
- 页码：7993
- 全文大小：2563K
- ISSN：1616-3028
文摘
A plasmonic gold (pGOLD) chip-based diagnosis of lung cancer is performed through multiplexed near-infrared detection of biomarkers in patient serum samples. On page 7994, J. Lou, K. Qian, and co-workers demonstrate that the device offers markedly improved limit-of-quantification, limit-of-detection, reproducibility, and higher diagnostic sensitivity and specificity over traditional biochips and Luminex technology currently in use in hospitals from just 10 μl of human serum.