Relationship between XspI Site Polymorphisms of LDL-R Gene and Serum IL-2 and IL-10 in Patients with Hypercholesterolemia

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• 作者：Mingming Zhang ; Yamin Lu ; Xin Liu ; Xiaobin Zhang ; Cuigai Zhang ; Wei Gao and Yanqing Tie
• 刊名：Journal of Clinical Laboratory Analysis
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：30
• 期：6
• 页码：1122-1127
• 全文大小：190K
• ISSN：1098-2825

文摘

Relationship has been identified in sporadic reports between polymorphisms and hypercholesterolemia. However, the relationship between inflammatory cytokines and polymorphism of low-density lipoprotein receptor (LDL-R) gene in hypercholesterolemia is unclear. This study aimed to explore the relationship and significance between polymorphisms of LDL-R gene and serum Interleukin-2 (IL-2), IL-10 in patients with hypercholesterolemia.