Pulmonary malignant melanoma with distant metastasis assessed by positron emission tomography-computed tomography

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• 作者：So Ri Kim ; Ha-Yong Yoon ; Gong Yong Jin ; Yeong Hun Choe ; Seung Yong Park and Yong Chul Lee
• 刊名：Thoracic Cancer
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：7
• 期：4
• 页码：503-507
• 全文大小：784K
• ISSN：1759-7714

文摘

Melanoma is a cutaneous malignant neoplasm of melanocytes. Primary malignant melanoma (MM) of the lung is very rare. Although previous reports have described the radiologic features of pulmonary MM, its rarity means that many factors are unknown. Thus, radiologic diagnosis is very difficult. Furthermore, there is little information regarding diagnostic application and/or the usefulness of [¹⁸F]-fluorine-2-fluoro-2-deoxy-D-glucose positron emission tomography-computed tomography (FDG-PET-CT) for primary pulmonary MM. A 69-year-old patient with a productive cough lasting three weeks was admitted to our hospital. Chest CT showed a large single mass with a multi-lobulated margin and homogeneous enhancement in the right upper lobe, which was subsequently diagnosed as a primary pulmonary MM with multiple metastases. On PET-CT images, the pulmonary mass and multiple bone lesions showed very increased uptakes of FDG. Considering that pulmonary metastasis from a mucocutaneous melanoma is the main differential diagnosis of primary pulmonary MM, systemic assessment of the whole body is more important than for other types of lung malignancies. This report introduces PET-CT as a useful diagnostic modality for pulmonary MM, especially in cases of distant multiple metastases.