TPGS-modified liposomes for the delivery of ginsenoside compound K against non-small cell lung cancer: formulation design and its evaluation in vitro and in vivo

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• 作者：Lei Yang ; Jin Xin ; Zhenhai Zhang ; Hongmei Yan ; Jing Wang ; E. Sun ; Jian Hou ; Xiaobin Jia and Huixia Lv
• 刊名：Journal of Pharmacy and Pharmacology
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：68
• 期：9
• 页码：1109-1118
• 全文大小：859K
• ISSN：2042-7158

文摘

This work aimed at preparing ginsenoside compound K (GCK)-loaded liposomes modified with TPGS (GCKT-liposomes) to enhance solubility and targeting capability of GCK, as well as inhibit the efflux of GCK from tumour cells.