ChemInform Abstract: Iron(III) Chloride-Catalyzed Tandem Aza-Prins/Friedel—Crafts Cyclization of 2-Arylethyl-2,3-butadienyl Tosylamides and Aldehydes — An Efficient Synthesis of Benzo[f]isoquinolines.
Convenient conditions using TmsCl as dehydrating agent and FeCl3 as the catalyst are developed for the tandem aza-Prins/Friedel—Crafts cyclization of allenes of type (I) and aldehydes.