Chlorogenic acid inhibits cholestatic liver injury induced by -naphthylisothiocyanate: involvement of STAT3 and NFκB signalling regulation
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- 作者：Zhen Tan ; Min Luo ; Julin Yang ; Yuqing Cheng ; Jing Huang ; Caide Lu ; Danjun Song ; Meiling Ye ; Manyun Dai ; Frank J. Gonzalez ; Aiming Liu and Bin Guo
- 刊名：Journal of Pharmacy and Pharmacology
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：68
- 期：9
- 页码：1203-1213
- 全文大小：1070K
- ISSN：2042-7158
文摘
Chlorogenic acid (CGA) is one of the most widely consumed polyphenols in diets and is recognized to be a natural hepatoprotective agent. Here, we evaluated the protective effect and the potential mechanism of CGA against ɑ-naphthylisothiocyanate (ANIT)-induced cholestasis and liver injury.