Evaluation of serum matrix metalloproteinase-3 as a biomarker for diagnosis of epilepsy
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- 作者：Rui Wanga ; 1046792011@qq.com" class="auth_mail" title="E-mail the corresponding author ; Guang Qun Zengb ; 568079831@qq.com" class="auth_mail" title="E-mail the corresponding author ; Xu Liua ; 304422707@qq.com" class="auth_mail" title="E-mail the corresponding author ; Rui Zhan Tongc ; sunnyt.r.zhan@163.com" class="auth_mail" title="E-mail the corresponding author ; Dong Zhoua ; 1 ; zhoudong66@yahoo.de" class="auth_mail" title="E-mail the corresponding author ; Zhen Honga ; 1 ; Hongzhengoog@aliyun.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：MMP-3 ; matrix metalloproteinase-3 ; EEG ; electroencephalogram ; ELISAs ; enzyme-linked immunosorbent assays ; AED ; anti-epileptic drug ; ROC ; Receiver Operator Characteristic ; MG ; Myasthenia gravis
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 August 2016
- 年：2016
- 卷：367
- 期：Complete
- 页码：291-297
- 全文大小：708 K
文摘
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Epilepsy patients have lower serum MMP-3 levels than healthy controls.
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Serum MMP-3 concentrations were significantly higher in males than in females.
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Serum MMP-3 levels were significantly increased as a function of age.
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Serum MMP-3 may be a potential biomarker for epilepsy if age and gender were considered.