Evaluating the effect of time process measures on appendectomy clinical outcomes

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• 作者：Paulette I. Abbas^a ; ^b ; Michelle Peterson^a ; Lindsay J. Stephens^a ; J. Ruben Rodriguez^a ; ^b ; Timothy C. Lee^a ; ^b ; Mary L. Brandt^a ; ^b ; Monica E. Lopez^a ; ^b ; ^{melopez@texaschildrens.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Pediatric surgery ; Appendicitis ; Time metrics ; Delayed appendectomy ; Surgical site infections
• 刊名：Journal of Pediatric Surgery
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：51
• 期：5
• 页码：810-814
• 全文大小：216 K

文摘

With varied reports on the impact of time to appendectomy on clinical outcomes, we examined the effects of pre-operative delays in pediatric acute appendicitis.

Methods

Children with acute appendicitis (January 2013–June 2014) were identified from a prospective database. Univariate analyses compared time metrics, patient characteristics, and disease severity with postoperative complications (POC) and organ space surgical site infection (OSSI), and multivariate logistic regression determined predictors of POC and OSSI.

Results

1211 patients underwent appendectomy. Median age was 10.4 years (IQR 7.8–13 years). 537 patients (45%) had complex appendicitis. Overall, POC was 11% (n = 133), and OSSI was 9% (n = 105). Neither time from presentation to appendectomy nor diagnosis to appendectomy increased POCs. On univariate analyses, operative time (OT) was longer in patients with POC (57 min (IQR 49–75) vs. 46 min (IQR 36–57), p < 0.001 and OSSI (60 min (IQR 51–80) vs. 46 min (IQR 37–57), p < 0.001. However, after adjusting for confounding factors, disease severity remained the most significant predictor of POC (OR 6.5, 95% CI 2.79–15.23) and OSSI (OR 76.6, 95% CI 7.87–745.65).

Conclusion

Pre-operative delays were not associated with increased POC or OSSI. The strongest predictor of POC or OSSI was disease severity, for which operative time may represent a surrogate.