Determination of parabens in domestic sewage by isotope-coded derivatization coupled with high performance liquid chromatography-tandem mass spectrometry

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• 作者：Dandan Che^a ; Zhiwei Sun^a ; ^{sunzhiw@126.com} ; Jie Cheng^a ; Kun Dou^a ; Zhongyin Ji^b ; ^c ; Guang Chen^c ; Guoliang Li^c ; Jinmao You^b ; ^c ; ^{jmyou6304@163.com}
• 关键词：Isotope-coded derivatization reagent ; Parabens ; High performance liquid chromatography ; Mass spectrometry
• 刊名：Microchemical Journal
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：130
• 期：Complete
• 页码：420-427
• 全文大小：1337 K
• 卷排序：130

文摘

Isotope-coded derivatization reagents were employed to determine parabens. The derivatization offers 1–2 orders of magnitude signal enhancement. The derivatization gives light/heavy isotope-labeled derivatives for each paraben. Accurate quantification was achieved with double internal standards calibration. The proposed method was applied to analyze parabens from wastewater samples.