Adipokinetic hormone receptor gene identification and its role in triacylglycerol metabolism in the blood-sucking insect Rhodnius prolixus
详细信息 查看全文
- 作者：Michele Alves-Bezerraa ; Iron F. De Paulaa ; Jorge M. Medinaa ; Gleidson Silva-Oliveiraa ; Jonas S. Medeirosa ; Gerd Gä ; deb ; Katia C. Gondima ; katia@bioqmed.ufrj.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Adipokinetic hormone (AKH) ; Adipokinetic hormone receptor (AKHR) ; Lipid mobilization ; Acyl-CoA-binding protein (ACBP) ; Glycerol-3-phosphate acyltransferase (GPAT)
- 刊名：Insect Biochemistry and Molecular Biology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：69
- 期：Complete
- 页码：51-60
- 全文大小：1554 K
文摘
- •
Rhodnius prolixus showed a single-copy gene coding an adipokinetic hormone (AKH) receptor, namely RhoprAkhr.
- •
RhoprAkhr was highly expressed in the fat body and flight muscle.
- •
The dsRNA-mediated knockdown of RhoprAkhr resulted in TAG accumulation in the fat body and flight muscle.
- •
The knockdown of Rhopr-AKHR as well as the injection of Rhopr-AKH resulted in altered gene expression in the fat body.