Relationship between adenosine deaminase polymorphism (c.22G > A) and oxidative stress in sickle cell anemia

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• 作者：Danilo Grü ; nig Humberto da Silva^a ; ^b ; ^{danilogrunig@hotmail.com} ; Edis Belini-Junior^a ; Lidiane de Souza Torres^a ; Jessika Viviani Okumura^a ; Willian Marcel Barberino^a ; Renan Garcia de Oliveira^a ; Vanessa Urbinatti Teixeira^a ; Clarisse Lopes de Castro Lobo^c ; Eduardo Alves de Almeida^b ; ^d ; Claudia Regina Bonini-Domingos^a
• 关键词：Hemoglobin S ; Adenosine ; Fetal hemoglobin ; Hydroxycarbamide
• 刊名：Meta Gene
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：11
• 期：Complete
• 页码：172-177
• 全文大小：560 K
• 卷排序：11

文摘

First report about ADA (22G > A) polymorphism in SCA from Rio de Janeiro State ADA frequency was lower than that reported for Caucasians. ADA frequency was higher than that expected for African descents. ADA does not play role in the disruption of sickle erythrocyte redox metabolism.