Protective efficacy of a peptide derived from a potential adhesin of Pseudomonas aeruginosa against corneal infection
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- 作者：Qing Yuana ; Yuting Wub ; Yiqiang Wangc ; Lin Chenb ; Mingli Qua ; Kangmin Duanb ; Ge Zhaoa ; d ; cathyge@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Adhesin ; Peptide ; Pseudomonas aeruginosa ; Protection ; Keratitis
- 刊名：Experimental Eye Research
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：143
- 期：Complete
- 页码：39-48
- 全文大小：2416 K
文摘
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We identified a potential novel adhesin on Pseudomonas aeruginosa surface.
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Derived Peptide Pc-EP significantly inhibits P. aeruginosa adhesion to corneal cells.
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Pc-EP stimulated the expression of some pro-inflammatory cytokines.
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Pc-EP effectively protects cornea against P. aeruginosa infection.